The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Sep. 30, 2016
Applicants:

Chin-yih Hong, Changhua, TW;

Herng-er Horng, New Taipei, TW;

Inventors:

Chin-Yih Hong, Changhua, TW;

Herng-Er Horng, New Taipei, TW;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C40B 40/06 (2006.01); C12N 15/10 (2006.01); C12N 15/115 (2010.01); C12Q 1/68 (2018.01); G01N 33/543 (2006.01); C12Q 1/6811 (2018.01);
U.S. Cl.
CPC ...
G01N 33/54333 (2013.01); C12N 15/1013 (2013.01); C12N 15/1072 (2013.01); C12Q 1/6811 (2013.01); C40B 40/06 (2013.01); G01N 33/5308 (2013.01);
Abstract

Multiplex immunoassays utilize the differential affinities among the conjugation pairs between the capture ligands and target analytes are proposed. Window magnetic-assisted rapid aptamer selection (window-MARAS) methods for selecting aptamers with desirable affinity toward the target analytes and methods for generating reagents for multiplex immunoassays or multiplex detection in one assay by utilizing the selected aptamers as capture ligands in reagents are described and used to demonstrate the feasibility of multiplex immunoassays based on the differential affinity of conjugation pairs between the capture ligands and target analytes.


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