The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Dec. 19, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
B. Chia Soo, Beverly Hills, CA (US);
Kang Ting, Beverly Hills, CA (US);
Zhong Zheng, Van Nuys, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 5/071 (2010.01); C07K 1/00 (2006.01); C12N 5/074 (2010.01); A61K 35/12 (2015.01); A61K 38/18 (2006.01); A61K 35/33 (2015.01); A61K 38/17 (2006.01); C12N 5/07 (2010.01); C07K 14/435 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); A61K 35/12 (2013.01); A61K 35/33 (2013.01); A61K 38/1709 (2013.01); A61K 38/18 (2013.01); C07K 14/435 (2013.01); C12N 5/06 (2013.01); C12N 2501/15 (2013.01); C12N 2501/998 (2013.01); C12N 2506/00 (2013.01); C12N 2506/13 (2013.01); C12N 2506/1307 (2013.01);
Abstract
The present invention provides a method of forming a fibromodulin (FMOD) reprogrammed (FReP) cell. The method comprises steps of treating a human cell with a cell culture medium comprising fibromodulin (FMOD) for a period ranging from a day to a month, and changing the cell culture medium regularly until a FMOD reprogrammed (FreP) cell forms; wherein the FreP cell expresses NANOG and does not form teratoma, and wherein the human cell is a fibroblastic cell.