The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

May. 25, 2016
Applicant:

Emd Millipore Corporation, Burlington, MA (US);

Inventors:

Philip J. Lee, Alameda, CA (US);

Terry Gaige, Hayward, CA (US);

Wei Hsuan (Jessie) Ho, Foster City, CA (US);

Assignee:

EMD Millipore Corporation, Burlington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); C12M 1/00 (2006.01); C12Q 1/02 (2006.01); C12M 1/34 (2006.01); B01L 3/00 (2006.01); B01L 7/00 (2006.01); C12M 1/107 (2006.01); C12M 1/02 (2006.01); C12M 1/36 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); B01L 3/502715 (2013.01); B01L 3/502761 (2013.01); B01L 3/563 (2013.01); B01L 7/00 (2013.01); C12M 23/36 (2013.01); C12M 23/40 (2013.01); C12M 29/10 (2013.01); C12M 29/24 (2013.01); C12M 41/14 (2013.01); C12M 41/18 (2013.01); C12M 41/34 (2013.01); C12M 41/36 (2013.01); C12M 41/40 (2013.01); C12M 41/46 (2013.01); C12M 41/48 (2013.01); C12Q 1/02 (2013.01); G01N 33/5005 (2013.01); G01N 33/574 (2013.01); B01L 2200/0689 (2013.01); B01L 2200/143 (2013.01); B01L 2200/146 (2013.01); B01L 2200/147 (2013.01); B01L 2300/048 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/14 (2013.01); B01L 2300/18 (2013.01); B01L 2300/1894 (2013.01); B01L 2400/0487 (2013.01);
Abstract

A micro-incubator manifold for improved microfluidic configurations and systems and methods of manufacture and operation for a manifold and automated microfluidic systems are disclosed. Various embodiments relate to assays, systems, and/or devices for culturing cells or other biologic material in controlled environments and are applicable to related fields generally using microfluidic systems. Particular embodiments involve configurations that can be used with various standard automated handling systems, with active or passive loading and perfusion of medium and to provide high-throughput multi-assay automated systems for culturing, viewing, and analyzing cell growth, invasion, movement, chemotaxis or other properties. More specifically, specific embodiments relate to heat control systems for microfluidic culture plates and other automated systems for culture plates.


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