The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Nov. 02, 2015
Applicant:
Leiden University Medical Center, Leiden, NL;
Inventors:
Mirjam H. M. Heemskerk, Leiden, NL;
J. H. Frederik Falkenburg, Leiden, NL;
Assignee:
LEIDEN UNIVERSITY MEDICAL CENTER, Leiden, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/64 (2006.01); C12N 9/90 (2006.01); A61K 39/00 (2006.01); C07K 14/47 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); A61K 39/0011 (2013.01); C07K 14/7051 (2013.01); C12N 5/0636 (2013.01); C12N 9/6472 (2013.01); C12N 9/90 (2013.01); C12Y 304/22062 (2013.01); C12Y 502/01008 (2013.01); A61K 39/00 (2013.01); C07K 2319/70 (2013.01); C12N 2510/00 (2013.01);
Abstract
The technology relates in part to compositions and methods for inducing an immune response against a Bob1 antigen. Provided are methods for treating hyperproliferative diseases by inducing an immune response against a Bob1 antigen; the immune response may be induced using a Bob1 polypeptide fragment, or by specifically targeting Bob1-expressing cells using T cell receptors directed against Bob1.