The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Dec. 17, 2014
Applicant:
Agency for Science, Technology and Research, Singapore, SG;
Inventors:
Jenefer Alam, Singapore, SG;
Soo Yei Ho, Singapore, SG;
Wei Ling Wang, Singapore, SG;
Athisayamani Jeyaraj Duraiswamy, Singapore, SG;
Assignee:
Agency for Science, Technology and Research, Singapore, SG;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01); A61P 19/02 (2006.01); A61P 19/04 (2006.01); A61P 17/06 (2006.01); A61P 9/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract
The present invention relates to dihydropyrazolo[1,5-a]pyrimidine compounds of formula I, defined herein, as WNT pathways modulators, processes for making them, and pharmaceutical compositions comprising them. Methods of treatment of conditions mediated by WNT pathway signalling including cancer, fibrosis, stem cell and diabetic retinopathy, rheumatoid arthritis, psoriasis and myocardial infarction, comprising the compounds of formula I are also provided.