The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Mar. 17, 2016
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Hai-Yun Xiao, Belle Mead, NJ (US);

Murali T. G. Dhar, Newtown, PA (US);

Jingwu Duan, Yardley, PA (US);

Bin Jiang, Bryn Mawr, PA (US);

Andrew J. Tebben, New Hope, PA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); C07D 487/06 (2006.01); A61P 37/00 (2006.01); A61P 29/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); A61P 29/00 (2018.01); A61P 37/00 (2018.01); C07D 487/06 (2013.01);
Abstract

Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is N; W is: (i) —(CRR)—; (ii) —(CRR)—Y—(CRR)—; Or (iii) —Y—(CRR)—Y—; and Y, R, R, R, R, R, R, x, and y are defined herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.


Find Patent Forward Citations

Loading…