The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Dec. 15, 2015
Applicant:
Laboratorios Del Dr. Esteve S.a., Barcelona, ES;
Inventors:
Carmen Almansa-Rosales, Barcelona, ES;
Monica Garcia-Lopez, Barcelona, ES;
Lourdes Garriga-Sanahuja, Barcelona, ES;
Ana Virginia Llorente-Fernandez, Barcelona, ES;
Assignee:
LABORATORIOS DEL DR. ESTEVE S.A., Barcelona, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/06 (2006.01); C07D 403/14 (2006.01); C07D 417/12 (2006.01); A61K 31/4523 (2006.01); A61K 31/496 (2006.01); C07D 417/14 (2006.01); C07D 401/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/4523 (2013.01); A61K 31/496 (2013.01); C07D 231/12 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 417/14 (2013.01);
Abstract
The present invention relates to 1-methylpyrazole-piperazine compounds having dual pharmacological activity towards both the sigma (σ) receptor, and the μ-opiod receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.