The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Oct. 24, 2016
Applicant:

Cancer Research Technology Limited, London, GB;

Inventors:

Keith Jones, Sutton Coldfield, GB;

Carl Rye, Sutton Coldfield, GB;

Nicola Chessum, Sutton Coldfield, GB;

Matthew Cheeseman, Sutton Coldfield, GB;

Adele E. Pasqua, Sutton Coldfield, GB;

Kurt G. Pike, Cambridge, GB;

Paul F. Faulder, Stockport, GB;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 319/18 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/08 (2006.01); C07D 491/056 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); C07D 319/18 (2013.01); C07D 405/14 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/08 (2013.01); C07D 491/056 (2013.01);
Abstract

The present invention relates to compounds of formula I as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.


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