The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Jun. 29, 2015
Applicants:

The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang, CN;

Versitech Ltd., Hong Kong, CN;

Inventors:

Weidong Pan, Guiyang, CN;

Yibin Feng, Hong Kong, CN;

Yazhou Liu, Guiyang, CN;

Ning Wang, Hong Kong, CN;

Lan Huang, Guiyang, CN;

Guangyi Liang, Guiyang, CN;

Maosheng Zhang, Guiyang, CN;

Tianlei Li, Guiyang, CN;

Huayong Lou, Guiyang, CN;

Zhanxing Hu, Guiyang, CN;

Sheng Liu, Guiyang, CN;

Peixue Cao, Guiyang, CN;

Jinghua Ruan, Guiyang, CN;

Junjie Lan, Guiyang, CN;

Chao Chen, Guiyang, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/18 (2006.01); A61K 31/4748 (2006.01); C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 491/16 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 491/16 (2013.01); C07D 491/18 (2013.01);
Abstract

The invention disclosed a compound of general formula (I), a single stereoisomer thereof, a mixture of stereoisomers thereof, and a prodrug, pharmaceutically acceptable salt and metabolite thereof, X, X, X, X, R, R, x, y and z being as defined in the present invention.


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