The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Sep. 17, 2015
Applicant:

Verseon Corporation, Fremont, CA (US);

Inventors:

Kevin Michael Short, Fremont, CA (US);

David Ben Kita, Fremont, CA (US);

Maria de los Angeles Estiarte-Martinez, Fremont, CA (US);

Son Minh Pham, Fremont, CA (US);

Assignee:

VERSEON CORPORATION, Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); C07D 401/04 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); C07D 409/14 (2013.01);
Abstract

There are provided inter alia pyrazolyl-substituted pyridone compounds, which exhibit biological activity, e.g., inhibitory action, against serine proteases, including thrombin and various kallikreins. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of serine proteases, including thrombin and various kallikreins.


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