The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Feb. 17, 2017
Applicant:
Ironwood Pharmaceuticals, Inc., Cambridge, MA (US);
Inventors:
Charles Kim, Ashburn, VA (US);
Takashi Nakai, Newton, MA (US);
Thomas Wai-Ho Lee, Lexington, MA (US);
Joel Moore, Lexington, MA (US);
Nicholas Robert Perl, Somerville, MA (US);
Jason Rohde, Andover, MA (US);
Rajesh R. Iyengar, West Newton, MA (US);
Ara Mermerian, Waltham, MA (US);
Angelika Fretzen, Somerville, MA (US);
Assignee:
Ironwood Pharmaceuticals, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); A61K 31/4155 (2006.01); A61K 45/06 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61K 31/522 (2006.01); A61K 31/5365 (2006.01); C07D 403/04 (2006.01); C07D 403/14 (2006.01); C07D 409/14 (2006.01); C07D 473/34 (2006.01); C07D 491/048 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 31/4155 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/497 (2013.01); A61K 31/506 (2013.01); A61K 31/522 (2013.01); A61K 31/5365 (2013.01); A61K 45/06 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 473/34 (2013.01); C07D 491/048 (2013.01); C07D 498/04 (2013.01);
Abstract
Compounds of Formula I are described. They are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds may be useful for treating, preventing or managing various disorders that are herein disclosed.