The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Aug. 28, 2014
Applicant:
Gilead Sciences, Inc., Foster City, CA (US);
Inventors:
Marc Labelle, Basking Ridge, NJ (US);
Thomas Boesen, Københaven Ø, DK;
Mukund Mehrotra, Winnipeg, CA;
Qasim Khan, Winnipeg, CA;
Farman Ullah, Winnipeg, CA;
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/79 (2006.01); C07D 413/12 (2006.01); A61K 31/44 (2006.01); A61K 31/443 (2006.01); A61K 31/444 (2006.01); A61K 31/4439 (2006.01); A61K 31/4545 (2006.01); A61K 31/496 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 213/79 (2013.01); A61K 31/44 (2013.01); A61K 31/443 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/496 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 405/12 (2013.01); C07D 413/12 (2013.01);
Abstract
The present application discloses compounds capable of modulating the activity of histone demethylases (HDMEs), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. cancer. The present application also discloses pharmaceutical compositions comprising said compounds and the use of such compounds as a medicament. The compounds take the form