The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Oct. 21, 2011
Ulrich H. Von Andrian, Chestnut Hill, MA (US);
Matteo Iannacone, Milan, IT;
Elena Tonti, Riccione, IT;
Elliott Ashley Moseman, Rockville, MD (US);
Ulrich H. von Andrian, Chestnut Hill, MA (US);
Matteo Iannacone, Milan, IT;
Elena Tonti, Riccione, IT;
Elliott Ashley Moseman, Rockville, MD (US);
President and Fellows of Harvard College, Cambridge, MA (US);
Abstract
The present invention demonstrates that bisphosphonates have an intrinsic adjuvant activity and directly stimulate B cell antibody secretion. Accordingly, the present invention provides vaccines comprising a bisphosphonate, methods for stimulating an immune response, enhancing the immunogenicicty of an immunogen, and methods of treating an infection, an autoimmune disease, an allergy, and/or a cancer using the same.