The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

Mar. 19, 2015
Applicants:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

University of Leeds, Leeds, GB;

Inventors:

Richard G. Vile, Rochester, MN (US);

Timothy J. Kottke, Oronoco, MN (US);

Jill M. Thompson, Stewartville, MN (US);

Jose S. Pulido, Rochester, MN (US);

Alan A. Melcher, Leeds, GB;

Peter Selby, Leeds, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 39/395 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61K 39/3955 (2013.01); C12N 7/00 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/70 (2013.01); C12N 2760/20243 (2013.01);
Abstract

This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.


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