The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 29, 2019

Filed:

May. 22, 2014
Applicant:

Yeda Research and Development Co. Ltd, Rehovot, IL;

Inventors:

Michal Eisenbach-Schwartz, Rehovot, IL;

Ester Yoles, Nahal Soreq, IL;

Inbal Benhar Bar-On, Rehovot, IL;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12N 5/078 (2010.01); A61K 35/15 (2015.01); A61K 39/00 (2006.01); C12N 5/0786 (2010.01); A61K 9/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 9/0048 (2013.01); A61K 35/17 (2013.01); A61K 39/0008 (2013.01); C12N 5/0645 (2013.01); A61K 2035/122 (2013.01); A61K 2039/5154 (2013.01);
Abstract

A monocyte subpopulation having a low relative amount, or substantially devoid, of CD3cells, CD19cells, CD56cells and optionally CD16cells is provided, wherein the monocyte subpopulation is for use in inhibition of neuronal degeneration, protection of neurons from glutamate toxicity or promotion of nerve regeneration in the retina or optic nerve, wherein the retina or optic nerve is damaged by a disease, disorder or condition of the eye, or for treatment of an inflammatory disease, disorder or condition of the eye.


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