The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Aug. 24, 2017
Applicant:
Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd., Jerusalem, IL;
Inventors:
Hadas Reuveni, Har Adar, IL;
Ehud Cohen, Jerusalem, IL;
Alexander Levitzki, Jerusalem, IL;
Shmuel Ben-Sasson, Jerusalem, IL;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/165 (2006.01); A61K 31/5415 (2006.01); C07D 279/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5415 (2013.01); A61K 31/165 (2013.01); C07D 279/08 (2013.01); A61K 2300/00 (2013.01);
Abstract
The present invention provides compounds acting as Insulin/IGF signaling modulators useful in the treatment of neurodegenerative diseases and disorders. The invention provides pharmaceutical compositions including such compounds, and methods of using these compounds and compositions for the treatment of neurodegenerative diseases, in particular neurodegenerative diseases caused by proteotoxicity such as Alzheimer's disease.