The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 29, 2019
Filed:
Sep. 21, 2014
Applicant:
Brenda Laster, Meitar, IL;
Inventors:
Brenda Laster, Meitar, IL;
Josef Kost, Omer, IL;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 31/555 (2006.01); A61K 31/409 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0024 (2013.01); A61K 31/409 (2013.01); A61K 31/555 (2013.01);
Abstract
Disclosed herein telomerase inhibitors and controlled-release formulations thereof, the use of telomerase-inhibiting porphyrins, especially metalloporphyrins, in the controlled-release intratumoral implants for the treatment of cancer. Provided herein also specific compositions of metalloporphyrins and poly-(lactic-co-glycolic)-acid copolymers, in various implantable forms, and methods of treatment cancer by administering the implants of the invention, alongside possible co-treatment with brachytherapy radioactive seeds to precipitate Auger effect of the metal atoms contained in the metalloporphyrins.