The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2019

Filed:

Feb. 19, 2018
Applicant:

Promega Corporation, Madison, WI (US);

Inventors:

Andrew S. Dixon, Verona, WI (US);

Lance Encell, Fitchburg, WI (US);

Mary Hall, Waunakee, WI (US);

Keith Wood, Mt. Horeb, WI (US);

Monika Wood, Mt. Horeb, WI (US);

Marie Schwinn, Madison, WI (US);

Brock F. Binkowski, Sauk City, WI (US);

Hicham Zegzouti, Madison, WI (US);

Nidhi Nath, Madison, WI (US);

Subhanjan Mondal, Middleton, WI (US);

Said Goueli, Fitchburg, WI (US);

Poncho Meisenheimer, San Luis Obispo, CA (US);

Thomas Kirkland, Atascadero, CA (US);

James Unch, Arroyo Grande, CA (US);

Dileep K. Pulukkunat, Middleton, WI (US);

Matthew Robers, Madison, WI (US);

Melanie Dart, Madison, WI (US);

Thomas Machleidt, Madison, WI (US);

Assignee:

Promega Corporation, Madison, WI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01); G01N 33/533 (2006.01); C07K 14/435 (2006.01); C12Q 1/66 (2006.01); C07K 7/08 (2006.01); A61K 51/08 (2006.01); C12N 9/02 (2006.01); G01N 33/542 (2006.01); G01N 33/58 (2006.01);
U.S. Cl.
CPC ...
G01N 33/533 (2013.01); A61K 51/08 (2013.01); C07K 7/08 (2013.01); C07K 14/43509 (2013.01); C12N 9/0069 (2013.01); C12Q 1/66 (2013.01); G01N 33/542 (2013.01); G01N 33/581 (2013.01);
Abstract

Provided herein are compositions and methods for the assembly of a bioluminescent complex from two or more non-luminescent (e.g., substantially non-luminescent) peptide and/or polypeptide units. In particular, bioluminescent activity is conferred upon a non-luminescent polypeptide via structural complementation with another, complementary non-luminescent peptide.


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