The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2019

Filed:

Oct. 08, 2015
Applicant:

T2 Biosystems, Inc., Lexington, MA (US);

Inventors:

Thomas Jay Lowery, Jr., Belmont, MA (US);

James Joseph Koziarz, Highland Park, IL (US);

Douglas Adam Levinson, Sherborn, MA (US);

David A. Berry, Brookline, MA (US);

Tuan A. Elstrom, Lake Bluff, IL (US);

Sonia Kumar, Brookline, MA (US);

Mark John Audeh, Brighton, MA (US);

Assignee:

T2 Biosystems, Inc., Lexington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 24/08 (2006.01); A61B 5/055 (2006.01); G01N 33/543 (2006.01); A61B 5/145 (2006.01); A61B 5/1486 (2006.01); A61B 10/00 (2006.01); A61B 17/00 (2006.01);
U.S. Cl.
CPC ...
G01N 24/08 (2013.01); A61B 5/055 (2013.01); G01N 33/54326 (2013.01); G01N 33/54346 (2013.01); A61B 5/14532 (2013.01); A61B 5/14865 (2013.01); A61B 10/0045 (2013.01); A61B 2017/00345 (2013.01); Y10T 436/143333 (2015.01); Y10T 436/144444 (2015.01); Y10T 436/147777 (2015.01); Y10T 436/16 (2015.01); Y10T 436/171538 (2015.01); Y10T 436/175383 (2015.01); Y10T 436/19 (2015.01); Y10T 436/201666 (2015.01); Y10T 436/204998 (2015.01); Y10T 436/207497 (2015.01); Y10T 436/24 (2015.01);
Abstract

Disclosed are magnetic nanosensors or transducers that permit measurement of a physical parameter in an analyte via magnetic reasonance measurements, in particular of non-agglomerative assays. More particularly, in certain embodiments, the invention relates to designs of nanoparticle reagents and responsive polymer coated magnetic nanoparticles. Additionally provided are methods of use of nanoparticle reagents and responsive polymer coated magnetic nanoparticles for the detection of a stimulus or an analyte with NMR detectors.


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