The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2019

Filed:

May. 04, 2010
Applicants:

Jan Kyhse-andersen, Værløse, DK;

Lars Winther, Smoerum, DK;

Inventors:

Jan Kyhse-Andersen, Værløse, DK;

Lars Winther, Smoerum, DK;

Assignee:

CHRETO ApS, Væløse, DK;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 1/22 (2006.01); C07K 1/36 (2006.01); C07K 1/32 (2006.01);
U.S. Cl.
CPC ...
C07K 1/22 (2013.01); C07K 1/32 (2013.01); C07K 1/36 (2013.01);
Abstract

The present invention relates to a process for purification of a target molecule, comprising the steps: (a) contacting a target molecule, and a population of target binding polypeptides (TBP), in solution for a sufficient time to allow complex formation; and (b) isolating the target from the complex from (a) by subsequent purification steps, wherein (i) the target binding polypeptides have at least two binding functionalities; a first binding functionality towards the target and a second binding functionality towards a catching ligand comprised in a solid support; and (ii) the first binding functionality comprises at least two binding sites for the target, and the target comp¬ rises at least two binding sites for the TBP.


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