The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2019

Filed:

Dec. 26, 2013
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Alexander Golberg, Boston, MA (US);

Martin L. Yarmush, Newton, MA (US);

Robert L. Sheridan, Lexington, MA (US);

William Gerald Austen, Weston, MA (US);

G. Felix Broelsch, Boston, MA (US);

Boris Rubinsky, El Cerrito, CA (US);

Michael Belkin, Tel Aviv, IL;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61N 1/32 (2006.01); A61N 1/36 (2006.01); A61N 1/04 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
A61N 1/36014 (2013.01); A61N 1/0464 (2013.01); A61N 1/0468 (2013.01); A61N 1/0476 (2013.01); A61N 1/0492 (2013.01); A61N 1/326 (2013.01); A61N 1/328 (2013.01); A61B 2018/00613 (2013.01); A61N 1/325 (2013.01); A61N 1/327 (2013.01);
Abstract

Systems and methods for controlling a tissue of a subject using applied pulsed electric fields. The system for controlling a therapy provided to a tissue of a subject using applied pulsed electric fields. The system includes an electrode assembly configured to engage a skin tissue of a subject to deliver a series of electric field pulses to the skin tissue and a user input configured to receive an operational instruction for the series of electric field pulses. The operational instruction defines at least one of a pulse duration, a pulse frequency, a pulse number, and a pulse amplitude. The system also includes at least one processor configured to access the operational instruction received by the user input and, using the operational instruction, create an electric field profile to be generated by the electrode assembly about the skin tissue of the subject to control a fibroblast characteristic while preserving a vascular perfusion in at least a portion of the skin tissue. The processor is also caused to control the electrode assembly using the electric field profile to deliver the series of electric field pulses to control the fibroblast characteristic.


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