The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 22, 2019

Filed:

Jan. 16, 2015
Applicant:

Cedars-sinai Medical Center, Los Angeles, CA (US);

Inventor:

Lali K. Medina-Kauwe, Los Angeles, CA (US);

Assignee:

CEDARS-SINAI MEDICAL CENTER, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 47/48 (2006.01); A61K 9/00 (2006.01); A61K 31/7105 (2006.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); C07K 14/005 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 9/0019 (2013.01); A61K 31/7105 (2013.01); A61K 47/64 (2017.08); A61K 47/6803 (2017.08); A61K 47/6851 (2017.08); A61K 47/6929 (2017.08); A61K 9/5169 (2013.01); C07K 14/005 (2013.01); C07K 2319/55 (2013.01); C07K 2319/74 (2013.01);
Abstract

Disclosed herein are drug delivery molecules that comprise a ligand that targets a cell surface molecule; a membrane penetration domain; and a payload binding domain; and pharmaceutical compositions comprising the same. Also disclosed are methods of treating cancer, inhibiting the progression of cancer, preventing cancer metastasis, and delivering a therapeutic compound to the brain in a subject in need thereof, the methods comprising identifying a subject in need thereof; providing a composition comprising the drug delivery molecule as disclosed herein; and administering an effective amount of the composition to the subject.


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