The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2019
Filed:
Oct. 28, 2014
Applicant:
Invectys, Paris, FR;
Inventors:
Pierre Langlade Demoyen, Neuilly-sur-Seine, FR;
Simon Wain-Hobson, Montigny-le-Bretonneux, FR;
Thierry Huet, Nogent sur Marne, FR;
Christelle Liard, Chatillon, FR;
Elodie Pliquet, Cachan, FR;
Assignee:
INVECTYS, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); C12N 9/1276 (2013.01); A61K 2039/53 (2013.01); C07K 2319/09 (2013.01); C07K 2319/35 (2013.01); C12Y 207/07049 (2013.01);
Abstract
The invention provides a nucleic acid construct comprising a sequence that encodes a human telomerase reverse transcriptase (hTERT) protein which is devoid of telomerase catalytic activity and of a nucleolar localization signal. The construct is useful triggering an immune response in a subject, against cells that overexpress telomerase, preferably dysplasia cells or tumor cells.