The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 22, 2019
Filed:
Jan. 27, 2016
Applicant:
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Inventors:
Yong Xu, Guangzhou, CN;
Xiaoqian Xue, Guangzhou, CN;
Yan Zhang, Guangzhou, CN;
Ming Song, Guangzhou, CN;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/92 (2006.01); A61K 31/403 (2006.01); C07D 403/12 (2006.01); A61K 31/422 (2006.01); A61K 31/454 (2006.01); A61K 31/5377 (2006.01); C07D 401/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/403 (2013.01); A61K 31/422 (2013.01); A61K 31/454 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 209/92 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract
The present invention relates to the technical field of medicinal chemistry, and in particular discloses a 2-oxo-1,2-dihydrobenzo[cd]indole compound and use thereof. The compound and pharmaceutically acceptable salt, isomer, racemate, prodrug, co-crystallized complex, hydrate, and solvate thereof can effectively inhibit the BET bromodomain receptor, and can be used for preparing a medicine for treating cancers, cell proliferative disorders, inflammatory diseases, and autoimmune disorders, sepsis, and viral infections.