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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10182987 B1

PDFFull Text
Date of Patent:
Jan. 22, 2019

Filed:

May. 18, 2015

Lipid membrane structure for intracellular delivery of sirna

Applicant:

National University Corporation Hokkaido University, Hokkaido, JP;

Inventors:

Hideyoshi Harashima, Hokkaido, JP;

Yusuke Sato, Hokkaido, JP;

Shota Warashina, Hokkaido, JP;

Hiroto Hatakeyama, Hokkaido, JP;

Mamoru Hyodo, Hokkaido, JP;

Takashi Nakamura, Hokkaido, JP;

Assignee:

NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Sapporo-shi, JP;

Attorney:

Birch, Stewart, Kolasch & Birch, LLP

Primary Examiner:

Jane J Zara

Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 9/127 (2006.01); C12N 15/113 (2010.01); C12N 15/88 (2006.01); A61K 9/12 (2006.01); A61K 47/18 (2017.01); A61K 31/7105 (2006.01); A61K 35/12 (2015.01); C07C 215/08 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61K 47/42 (2017.01); A61K 47/48 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
A61K 9/12 (2013.01); A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 31/7105 (2013.01); A61K 35/12 (2013.01); A61K 39/0012 (2013.01); A61K 39/39 (2013.01); A61K 47/18 (2013.01); A61K 47/42 (2013.01); A61K 47/48 (2013.01); A61K 47/48238 (2013.01); A61K 47/48815 (2013.01); A61K 47/48838 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); A61K 48/0041 (2013.01); C07C 215/08 (2013.01); C12N 15/113 (2013.01); C12N 15/88 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/6018 (2013.01); A61K 2039/6025 (2013.01); C12N 15/00 (2013.01); C12N 15/09 (2013.01); C12N 15/63 (2013.01);
Abstract

A lipid membrane structure encapsulating an siRNA inside thereof and containing a lipid compound of the formula (I) as a lipid component (Rand Rrepresent CH—(CH)—CH═CH—CH—CH═CH—(CH)—, n represents an integer of 3 to 5, m represents an integer of 6 to 10, p represents an integer of 2 to 7, and Rand Rrepresent a Calkyl group or a Calkenyl group.

Find Patent Forward Citations

Harashima, Hideyoshi. (2019). Lipid membrane structure for intracellular delivery of sirna (U.S. Patent No. 10182987). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10182987

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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