The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2019

Filed:

Feb. 05, 2018
Applicant:

Fluidigm Corporation, South San Francisco, CA (US);

Inventors:

Dmitry R. Bandura, Ontario, CA;

Vladimir I. Baranov, Ontario, CA;

Scott D. Tanner, Ontario, CA;

Assignee:

Fluidigm Corporation, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01J 49/04 (2006.01); G01N 15/14 (2006.01); H01J 49/00 (2006.01); G01N 15/00 (2006.01);
U.S. Cl.
CPC ...
G01N 15/1404 (2013.01); H01J 49/004 (2013.01); H01J 49/04 (2013.01); H01J 49/0431 (2013.01); G01N 2015/0065 (2013.01); G01N 2458/15 (2013.01);
Abstract

A method for cellular analysis of cellular particles tagged with elemental tags, such as lanthanide-based elemental tags. Particles or element tags associated with particles can be vaporized, atomized, and ionized, such as with an inductively coupled plasma device or a glow discharge device. The vaporized, atomized, and ionized particles or element tags can be analyzed using mass spectrometry, such as using a time of flight mass spectrometer or a magnetic sector mass spectrometer. The amount of at least one element in individual particles can be measured through mass analysis. The amount of many different tags, for example at least five different tags, can be measured at the same time to facilitate multi-parametric analysis of cells and other particles. The vaporized, atomized, and ionized particles or element tags can be pretreated in an ion pretreatment system to filter out low mass ions, such as using a high-pass mass filter or a bandpass mass filter, to allow the elemental tags to pass therethrough.


Find Patent Forward Citations

Loading…