The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
Apr. 30, 2010
Steven Shak, Hillsborough, CA (US);
Drew Watson, Los Altos, CA (US);
Xitong LI, Mountain View, CA (US);
Lawrence Lee, San Francisco, CA (US);
Kim Clark-langone, Sunnyvale, CA (US);
Steven Shak, Hillsborough, CA (US);
Drew Watson, Los Altos, CA (US);
Xitong Li, Mountain View, CA (US);
Lawrence Lee, San Francisco, CA (US);
Kim Clark-Langone, Sunnyvale, CA (US);
Genomic Health, Inc., Redwood City, CA (US);
Abstract
Algorithm-based molecular assays that involve measurement of expression levels of prognostic and/or predictive genes, or co-expressed genes thereof, from a biological sample obtained from a cancer patient, and analysis of the measured expression levels to provide information concerning the likelihood of recurrence of colorectal cancer and/or the likelihood of a beneficial response to chemotherapy for the patient are provided herein. Methods of analysis of gene expression values of prognostic and/or predictive genes, as well as methods of identifying gene expression-tumor region ratios, tumor-associated stromal surface area, and gene cliques, i.e. genes that co-express with a validated biomarker and thus may be substituted for that biomarker in an assay, are also provided.