The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
May. 02, 2018
Applicant:
Sutro Biopharma, Inc., South San Francisco, CA (US);
Inventors:
Erik S. Zimmerman, Pacifica, CA (US);
Christopher Thanos, Tiburon, CA (US);
Assignee:
SUTRO BIOPHARMA, INC., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 9/93 (2013.01); C12P 21/02 (2013.01); C12Y 601/01 (2013.01); C12Y 601/01001 (2013.01);
Abstract
The invention provides methods and compositions for a mutein aminoacyl-tRNA synthetase that preferentially charges a tRNA with a non-natural amino acid. Also provided are methods for incorporating the non-natural amino acids, pyridinyl-amino tetrazine amino acids, into a protein, and further conjugating a biologically active adduct to the pyridinyl-amino tetrazine.