The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2019

Filed:

Mar. 29, 2016
Applicants:

Roche Molecular Systems, Inc., Pleasanton, CA (US);

Ventana Medical Systems, Inc., Tucson, AZ (US);

Inventors:

Monika Soukupova, Wessobrunn, DE;

Michael Schraeml, Penzberg, DE;

Birgit Bossenmaier, Seefeld, DE;

Patrick C. Roche, Tucson, AZ (US);

Michael Gerg, Munich, DE;

Sebastian Dziadek, Benediktbeuern, DE;

Assignees:

VENTANA MEDICAL SYSTEMS, INC., Tucson, AZ (US);

ROCHE MOLECULAR SYSTEMS, INC., Pleasanton, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/32 (2006.01); C07K 16/30 (2006.01); G01N 1/30 (2006.01); G01N 33/574 (2006.01); G01N 33/74 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); C07K 16/3023 (2013.01); C07K 16/3046 (2013.01); C07K 16/32 (2013.01); G01N 1/30 (2013.01); G01N 33/57492 (2013.01); G01N 33/74 (2013.01); C07K 2317/33 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); G01N 2001/302 (2013.01); G01N 2333/71 (2013.01);
Abstract

The present invention relates to isolated antibodies, or an antigen portions thereof, which bind to human HER3. The novel antibodies are of great utility since they allow for the sensitive and specific detection of human HER3. Detection of human HER3 is, e.g., possible in a tissue sample, even when such tissue sample is a formalin-fixed paraffin embedded tissue (FFPET) sample.


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