The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2019

Filed:

Dec. 10, 2013
Applicant:

Yamasa Corporation, Choshi-shi, JP;

Inventor:

Kohei Yamada, Choshi, JP;

Assignee:

YAMASA CORPORATION, Choshi-shi, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 19/10 (2006.01); A61K 31/7072 (2006.01); A61K 31/7105 (2006.01); C07F 9/6558 (2006.01);
U.S. Cl.
CPC ...
C07H 19/10 (2013.01); A61K 31/7072 (2013.01); A61K 31/7105 (2013.01); C07F 9/65586 (2013.01);
Abstract

A method for producing P,P-di(uridine 5'-)tetraphosphate (UPU) that can avoid reduction of the synthetic efficiency without using UTP free is developed. A method for producing UPU comprising reacting a phosphoric acid-activating compound represented by formula [II] or [III] with a phosphoric acid compound selected from the group consisting of UMP, UDP, UTP and a pyrophosphoric acid or a salt thereof (excluding UTP free) in water or a hydrophilic organic solvent, in the presence of a metal ion selected from the group consisting of an iron (II) ion, an iron (III) ion, a trivalent aluminum ion, a trivalent lanthanum ion, and a trivalent cerium ion.


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