The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
Sep. 12, 2016
Christel Jeanne Marie Menet, Mechelen, BE;
Oscar Mammoliti, Mechelen, BE;
Javier Blanc, Mechelen, BE;
Mislav Orsulic, Zagreb, HR;
Maja Roscic, Zagreb, HR;
Christel Jeanne Marie Menet, Mechelen, BE;
Oscar Mammoliti, Mechelen, BE;
Javier Blanc, Mechelen, BE;
Mislav Orsulic, Zagreb, HR;
Maja Roscic, Zagreb, HR;
GALAPAGOS NV, Mechelen, BE;
Abstract
The present invention discloses compounds according to Formula I: wherein Cy, R, L, R, R, R, L, and Rare as defined herein. Novel benzimidazoles according to Formula I, able to inhibit JAK are disclosed, these compounds may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, allergic diseases, inflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or hypersecretion of interferons.