The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 15, 2019

Filed:

May. 20, 2016
Applicants:

Genentech, Inc., South San Francisco, CA (US);

Xenon Pharmaceuticals Inc., Burnaby, CA;

Inventors:

Sultan Chowdhury, Burnaby, CA;

Christoph Martin Dehnhardt, Burnaby, CA;

Abid Hasan, Burnaby, CA;

Ivan William Hemeon, Burnaby, CA;

Qi Jia, Burnaby, CA;

Jun Li, South San Francisco, CA (US);

Zhiguo Liu, Shanghai, CN;

Daniel F. Ortwine, South San Francisco, CA (US);

Brian Safina, South San Francisco, CA (US);

Daniel Sutherlin, South San Francisco, CA (US);

Shaoyi Sun, Burnaby, CA;

Andrew D. White, Shanghai, CN;

Wei Gong, Burnaby, CA;

Alla Yurevna Zenova, Burnaby, CA;

Jiuxiang Zhu, Shanghai, CN;

Assignees:

GENENTECH, INC., South San Francisco, CA (US);

XENON PHARMACEUTICALS INC., Burnaby, BC, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/00 (2006.01); A61K 31/00 (2006.01); C07D 211/22 (2006.01); C07D 211/48 (2006.01); C07D 211/34 (2006.01); C07D 405/08 (2006.01); C07D 401/12 (2006.01); C07D 401/08 (2006.01); C07D 211/42 (2006.01); C07D 221/20 (2006.01); C07D 401/04 (2006.01); C07D 211/38 (2006.01); C07D 211/62 (2006.01);
U.S. Cl.
CPC ...
C07D 211/22 (2013.01); C07D 211/34 (2013.01); C07D 211/38 (2013.01); C07D 211/42 (2013.01); C07D 211/48 (2013.01); C07D 211/62 (2013.01); C07D 221/20 (2013.01); C07D 401/04 (2013.01); C07D 401/08 (2013.01); C07D 401/12 (2013.01); C07D 405/08 (2013.01);
Abstract

The invention provides compounds having activity as sodium channel (e.g., NaV1.7) inhibitors that are useful for treating sodium channel-mediated diseases or conditions, such as pain, as well as other diseases and conditions associated with the mediation of sodium channels, and compositions containing such compounds and methods for using such compounds and compositions.


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