The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
Jan. 06, 2016
Applicant:
Glaxosmithkline Biologicals SA, Rixensart, BE;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/095 (2006.01); A61K 49/00 (2006.01); C12N 9/10 (2006.01); C07K 14/22 (2006.01); C12N 1/20 (2006.01); C12N 1/38 (2006.01);
U.S. Cl.
CPC ...
A61K 39/095 (2013.01); C07K 14/22 (2013.01); C12N 1/20 (2013.01); C12N 1/38 (2013.01); C12N 9/1085 (2013.01); A61K 2039/523 (2013.01); C12Y 205/01072 (2013.01);
Abstract
A first aspect of the invention provides meningococcal outer membrane vesicles in which NHBA is over-expressed. A second aspect of the invention provides meningococcal outer membrane vesicles in which NadA is over-expressed. A third aspect of the invention provides a panel of bacterial strains, each member of which is isogenic except for a single gene which in each strain encodes a different variant antigen of interest.