The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
May. 24, 2012
Method for inducing an immune response for treatment of cancer and autoimmune diseases or conditions
Daniel H. Zimmerman, Bethesda, MD (US);
Eyal Talor, Baltimore, MD (US);
Kenneth Rosenthal, Akron, OH (US);
Daniel H. Zimmerman, Bethesda, MD (US);
Eyal Talor, Baltimore, MD (US);
Kenneth Rosenthal, Akron, OH (US);
Cel-Sci Corporation, Vienna, VA (US);
Abstract
The invention is related to peptide constructs, i.e., polypeptides obtained by linking together two or more peptides based on or derived from different molecules, which are useful in the treatment or prevention of cancer or the treatment of autoimmune diseases and compositions containing same, methods for producing same, and methods for using same; wherein the peptide constructs have the formula P-x-Pwhere Pis a peptide associated with forms of cancer or an autoimmune condition and Pis a peptide which will bind to a class of immune cells such as dendritic cells. The peptide construct can cause the maturation of immature dendritic cells to a more mature state. The peptide construct or the more mature dendritic cells can be administered to a subject to a modulate or to initiate an immune response against cancer cells, and can be used with dyes, radioisotopes, or therapeutic agents for detection of the immune target and/or treatment of cancer and autoimmune conditions.