The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 15, 2019
Filed:
Oct. 02, 2014
Applicant:
Anthrogenesis Corporation, Warren, NJ (US);
Inventors:
Jodi P. Gurney, Chicago, IL (US);
Xiaokui Zhang, Livingston, NJ (US);
Stacy Herb, Mountain Top, PA (US);
Robert J. Hariri, Bernardsville, NJ (US);
Assignee:
Celularity, Inc., Warren, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/50 (2015.01); A61K 35/51 (2015.01); A61K 35/12 (2015.01); A61K 35/28 (2015.01); C12N 5/0789 (2010.01);
U.S. Cl.
CPC ...
A61K 35/50 (2013.01); A61K 35/12 (2013.01); A61K 35/28 (2013.01); A61K 35/51 (2013.01); C12N 5/0647 (2013.01); A61K 2035/122 (2013.01); A61K 2035/124 (2013.01);
Abstract
Provided herein are methods of treatment comprising administering to a subject, e.g., a human subject, mononuclear cells from human placental perfusate and hematopoietic cells, and compositions comprising them, and their uses to establish chimerism, engraft tissue (e.g., blood), reduce the severity or duration of graft versus host disease, and treat or ameliorate symptoms of metabolic disorders and hematologic disorders, such as hematologic malignancies.