The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Nov. 02, 2015
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Joshua A. Burnett, Taunton, MA (US);

James Usowicz, Webster, MA (US);

Marc Lemelin, Douglas, MA (US);

Lucas O. Tiziani, Seekonk, MA (US);

Aaron Lebeau, Taunton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 30/32 (2006.01); G01N 30/80 (2006.01); G01N 30/02 (2006.01); G01N 30/78 (2006.01);
U.S. Cl.
CPC ...
G01N 30/32 (2013.01); G01N 30/80 (2013.01); G01N 30/78 (2013.01); G01N 2030/027 (2013.01); G01N 2030/324 (2013.01); G01N 2030/328 (2013.01);
Abstract

Apparatus and method measure the flow rate of fluid for use in calibrating fraction collection in a chromatography system. An injector inserts a detectable substance into a flow of fluid. A first detector, disposed in a path of the flow of liquid with the substance, produces a signal in response to detecting the substance in the flow of fluid. A second detector, disposed downstream from the first detector in the path of the flow of fluid with the substance, produces a signal in response to detecting the substance in the flow of fluid. A computing system receives each signal produced by the first and second detectors upon detecting the substance in the flow of fluid, and computes a volumetric flow rate of the flow of fluid based on a time interval between the signals and a volume of the path between the first and second detectors.


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