The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
May. 26, 2016
Applicant:
Korea Advanced Institute of Science and Technology, Daejeon, KR;
Inventors:
Byong-Seok Choi, Daejeon, KR;
Mi Kyung Lee, Daejeon, KR;
Janghyun Lee, Daejeon, KR;
Suk-Jo Kang, Daejeon, KR;
Eun Byeol Park, Daejeon, KR;
Assignee:
KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, Daejeon, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/713 (2006.01); A61K 48/00 (2006.01); C12N 15/117 (2010.01);
U.S. Cl.
CPC ...
C12N 15/117 (2013.01); C12N 2310/17 (2013.01); C12N 2310/315 (2013.01); C12N 2310/317 (2013.01); C12N 2310/52 (2013.01); C12N 2310/533 (2013.01);
Abstract
The present disclosure provides an RNA oligonucleotide having a helical bend structure and a use thereof. Specifically, double strands formed by a complementary binding of two sequences have a helical bend structure in the RNA oligonucleotide. The RNA oligonucleotide can increase the expression of interferon-β or ISG56 and thus can be used as an immune system enhancer.