The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Apr. 07, 2017
Applicant:
Polytherics Limited, Cambridge, GB;
Inventors:
Antony Robert Godwin, London, GB;
Stephen James Brocchini, Welwyn Garden, GB;
Assignee:
POLYTHERICS LIMITED, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); C07C 317/50 (2006.01); C07C 315/04 (2006.01); C08G 65/333 (2006.01); C08G 65/334 (2006.01); A61K 38/21 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); A61K 38/212 (2013.01); A61K 38/215 (2013.01); A61K 47/60 (2017.08); C07C 315/04 (2013.01); C07C 317/50 (2013.01); C08G 65/3348 (2013.01); C08G 65/33334 (2013.01); C08G 65/33396 (2013.01); C07K 2317/24 (2013.01); C07K 2317/55 (2013.01); C08G 2650/30 (2013.01); C08G 2650/50 (2013.01); C08L 2203/02 (2013.01);
Abstract
The invention provides compound of the general formula: in which each X independently represents a polymer chain; n represents an integer greater than 1; Q represents a linker; Y represents an amide group; and Z represents either —CH.(CHL)or —C(CHL)(═CH), in which each L independently represents a leaving group. The compounds are useful reagents for the conjugation of polymers to proteins, the resulting conjugates being novel and also forming part of the invention.