The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Feb. 22, 2012
Zhiqian Zhang, Beijing, CN;
Wei Zhao, Beijing, CN;
Limin Wang, Beijing, CN;
Haibo Han, Beijing, CN;
Baocai Xing, Beijing, CN;
Zhiqian Zhang, Beijing, CN;
Wei Zhao, Beijing, CN;
Limin Wang, Beijing, CN;
Haibo Han, Beijing, CN;
Baocai Xing, Beijing, CN;
Beijing Institute for Cancer Research, Beijing, CN;
Abstract
Disclosed is a method for searching, identifying, or validating a marker CACNA2D1 of tumor-initiating cells. The method comprises a step of immunizing an animal using HEP-12 cells originating from a recurrent tumor and rich in originating cells. Also disclosed is a monoclonal antibody specially recognizing CACNA2D1 or antigen-binding fragments thereof, and the use thereof for treating or preventing tumors or diseases or conditions related to CACNA2D1.