The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Nov. 13, 2017
Toxoid peptides derived from phenol soluble modulin, delta toxin, superantigens, and fusions thereof
Integrated Biotherapeutics, Inc., Rockville, MD (US);
Mohammad Javad Aman, Rockville, MD (US);
Rajan Prasad Adhikari, Gaithersburg, MD (US);
Sergey Shulenin, Point of Rocks, MD (US);
Frederick Wayne Holtsberg, Taneytown, MD (US);
Hatice Karauzum, Rockville, MD (US);
INTEGRATED BIOTHERAPEUTICS, INC., Rockville, MD (US);
Abstract
The present disclosure provides immunogenic compositions useful in prevention and treatment ofinfection. In particular, the disclosure provides delta toxin and phenol-soluble modulin peptides as well as mutants, fragments, variants or derivatives thereof. The disclosure further provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal proteins, e.g., DT, PSM, alpha hemolysin, leukocidin, superantigen, or any fragments, variants, derivatives, or mutants thereof fused together as a single polypeptide in any order.