The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Oct. 24, 2017
Applicant:
Cleave Biosciences, Inc., Burlingame, CA (US);
Inventors:
Han-Jie Zhou, Foster City, CA (US);
David Wustrow, Los Gatos, CA (US);
Assignee:
Cleave Biosciences, Inc., Burlingame, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 491/052 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 491/052 (2013.01);
Abstract
The present invention is directed to certain fused pyrimidines having a homo or hetero cyclopentyl, cyclohexyl or cycloheptyl ring as the pyrimidine fusion partner; having an amino benzyl or substituted amino benzyl group at the 4 position of the pyrimidine ring; and a 5:6 heterobicyclo ring with at least one N, O or S at the 2 position of the pyrimidine ring. These compounds are useful for treatment of cancer by inhibition of the p97 complex.