The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Sep. 24, 2017
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Seetharamaiah Setty Sudarshan Naremaddepalli, Bangalore, IN;
Pottayil Govindan Nair Sasikumar, Bangalore, IN;
Muralidhara Ramachandra, Bangalore, IN;
Seetharamaiah Setty Sudarshan Naremaddepalli, Bangalore, IN;
Aurigene Discovery Technologies Limited, Bangalore, IN;
Abstract
The present invention relates to synthetic methods for 1,2,4-oxadiazole compounds. The general synthetic scheme is: Rrepresents −CHOBu or −CH(CH)OBu, Rrepresents −CHC(O)NHCPh, −CHCHC(O)NHCPh, −CHC(O)OBu, or −CHCHC(O)OBu, and Aaa is an amino acid residue selected from Thr and Ser; wherein the C-terminus thereof is esterified, and wherein the hydroxy moiety of the side chain of Thr or Ser is substituted with tbutyl; the base is triethylamine; and the solvent is tetrahydrofuran.