The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Nov. 13, 2014
Applicant:

Zata Pharmaceuticals, Inc., Worcester, MA (US);

Inventor:

David R. Tabatadze, Worcester, MA (US);

Assignee:

ZATA PHARMACEUTICALS, INC., Worcester, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 203/12 (2006.01); A61L 2/16 (2006.01);
U.S. Cl.
CPC ...
C07D 203/12 (2013.01); A61L 2/16 (2013.01);
Abstract

Described herein are compositions and compounds having one or more aziridinyl groups, and methods of making the same. The compounds can also have one or more nitrogen atoms that each can be positively charged. The composition and compounds can inactivate one or more nucleic acid molecules (e.g. a DNA and/or a RNA from a pathogen) in a sample. The sample can comprise a blood or blood product (e.g., donated blood). The compositions and compounds can inactivate any nucleic acid present in a blood or blood product, thereby making the blood or blood product safe for use (e.g., in a transfusion).


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