The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Mar. 01, 2017
Applicant:
Mamoun M Alhamadsheh, Stockton, CA (US);
Inventors:
Mamoun M. Alhamadsheh, Stockton, CA (US);
Miki S. Park, Stockton, CA (US);
William K. Chan, Elk Grove, CA (US);
Xiaoling Li, Dublin, CA (US);
Sravan C. Penchala, Stockton, CA (US);
Mark R. Miller, Stockton, CA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); A61K 31/47 (2006.01); A61K 49/00 (2006.01); A61K 31/00 (2006.01); A61K 47/54 (2017.01); A61K 38/00 (2006.01); C07D 231/12 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
A61K 47/64 (2017.08); A61K 31/00 (2013.01); A61K 31/4745 (2013.01); A61K 47/545 (2017.08); A61K 49/0052 (2013.01); A61K 38/00 (2013.01); C07D 231/12 (2013.01);
Abstract
A delivery system for active agents, and methods of making and using the systems, are provided. The delivery systems have (i) a ligand that is selective for an endogeneous plasma protein in the serum of a subject; and, (ii) a linker configured for operatively attaching the ligand covalently to an active agent to increase the half-life of the active agent in the serum.