The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Feb. 27, 2013
Applicant:
Amunix Operating Inc., Mountain View, CA (US);
Inventors:
Volker Schellenberger, Palo Alto, CA (US);
Vladimir Podust, Castro Valley, CA (US);
Chia-Wei Wang, Milpitas, CA (US);
Bryant McLaughlin, Millbrae, CA (US);
Bee-Cheng Sim, Mountain View, CA (US);
Sheng Ding, Redwood City, CA (US);
Chen Gu, Fremont, CA (US);
Assignee:
Amunix Operating Inc., Mountain View, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 47/48 (2006.01); C07K 5/02 (2006.01); A61K 49/00 (2006.01); A61K 38/24 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/48246 (2013.01); A61K 38/24 (2013.01); A61K 47/64 (2017.08); A61K 49/0032 (2013.01); A61K 49/0052 (2013.01); A61K 49/0056 (2013.01); C07K 5/0205 (2013.01);
Abstract
The present invention relates to extended recombinant polypeptide (XTEN) compositions, conjugate compositions comprising XTEN and XTEN linked to cross-linkers useful for conjugation to pharmacologically active payloads, methods of making highly purified XTEN, methods of making XTEN-linker and XTEN-payload conjugates, and methods of using the XTEN-cross-linker and XTEN-payload compositions.