The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Mar. 12, 2014
Applicant:

Hercules Incorporated, Wilmington, DE (US);

Inventors:

Divya Tewari, West Chester, PA (US);

Yevgeniya A. Titova, Wilmington, DE (US);

Brad Beissner, Wilmington, DE (US);

Thomas Durig, Chadds Ford, PA (US);

Assignee:

ISP INVESTMENTS LLC, Wilmington, DE (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/32 (2006.01); A61K 9/20 (2006.01); A61K 47/38 (2006.01); A61K 31/522 (2006.01); A61J 3/10 (2006.01); A61K 47/02 (2006.01); C09D 139/06 (2006.01); C09J 139/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/32 (2013.01); A61J 3/10 (2013.01); A61K 9/2009 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 31/522 (2013.01); A61K 47/02 (2013.01); A61K 47/38 (2013.01); C09D 139/06 (2013.01); C09J 139/06 (2013.01);
Abstract

An excipient composition having good bulk density and improved flow characteristics is provided. The present invention particularly provides a coprocessed excipient composition and a method of producing the same. The coprocessed excipient comprises cellulose derived polymer and a deagglomerated coprocessing agent. The coprocessing agent is fumed silica, colloidal silica or silicon dioxide. The coprocessed excipient is prepared in a continuous process and has excellent compactability and improved flow property as measured by Johanson flow rate number increase from 1.1 to 5.0 fold, is characterized by a Brookfield cohesion factor of less than 0.2 kPa and a bulk density of at least 0.249 g/ml.


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