The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Apr. 28, 2015
Kristi L. Kiick, Rising Sun, MD (US);
April M. Kloxin, Landenberg, PA (US);
Prathamesh M. Kharkar, Newark, DE (US);
Raja Sivamani, Sacramento, CA (US);
Emanual Maverakis, Sacramento, CA (US);
Kristi L. Kiick, Rising Sun, MD (US);
April M. Kloxin, Landenberg, PA (US);
Prathamesh M. Kharkar, Newark, DE (US);
Raja Sivamani, Sacramento, CA (US);
Emanual Maverakis, Sacramento, CA (US);
University of Delaware, Newark, DE (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
A responsive hydrogel-based material may be used as a carrier system for the in situ delivery of various cargo substances, including bioactive moieties. The hydrogel structure, which includes photodegradable and thioether moieties in its three dimensional network, enables finely tuned local release of cargo substances as a function of the in vivo tissue environment (e.g., enzyme concentration or reducing environment) and externally applied stimuli (e.g., light) by selective spatiotemporal hydrogel degradation.