The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2019

Filed:

Jul. 20, 2016
Applicant:

Flow Pharma, Inc., East Palo Alto, CA (US);

Inventors:

Reid M. Rubsamen, Alamo, CA (US);

David Earl Heckerman, Santa Monica, CA (US);

Assignee:

FLOW PHARMA, INC., East Palo Alto, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/385 (2006.01); A61K 9/16 (2006.01); A61K 39/39 (2006.01); A61K 9/51 (2006.01); A61K 39/245 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/385 (2013.01); A61K 9/1647 (2013.01); A61K 9/5153 (2013.01); A61K 39/245 (2013.01); A61K 39/39 (2013.01); C12N 7/00 (2013.01); A61K 2039/55511 (2013.01); A61K 2039/55555 (2013.01); A61K 2039/55572 (2013.01); A61K 2039/57 (2013.01); A61K 2039/6093 (2013.01); A61K 2039/70 (2013.01); C12N 2710/16134 (2013.01);
Abstract

A composition as disclosed is comprised of a plurality of groups of particles. The particles are comprised of a biocompatible polymer which may be a co-polymer such as PLGA combined with a peptide of a sequence of interest, e.g. a sequence which corresponds to a sequence presented on a surface of a cell infected with a virus. A plurality of different groups of particles are provided in the formulation wherein the particles within any single group include peptides of identical amino acid sequence. The particles are sized such that they are sufficiently large so as to prevent more than the contents of a single particle from being presented to a single immune system cell.


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