The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Aug. 28, 2014
Applicant:
Promethera Biosciences S.a./n.v., Mont-Saint-Guibert, BE;
Inventors:
Etienne Sokal, Hoeilaart, BE;
Sarah Snykers, Lede, BE;
Tuba Baran, Fontaine-l'Eveque, BE;
Kris Gellynck, Saint-Gilles, BE;
Assignee:
Promethera Biosciences S.A./N.V., Mont-Saint-Guibert, BE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/407 (2015.01); G01N 33/50 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61K 35/407 (2013.01); C12N 5/0672 (2013.01); G01N 33/5023 (2013.01); G01N 33/5067 (2013.01); C12N 2501/11 (2013.01); C12N 2501/12 (2013.01); C12N 2501/734 (2013.01); C12N 2533/54 (2013.01);
Abstract
Novel adult liver progenitor cells (called H2Stem Cells) have been have been characterized on the basis of a series of biological activities and markers. Methods for producing H2Stem Cells allow providing such cells in the form of adherent cells and three-dimensional cell clusters in suspension that can be differentiated into cells having strong liver-specific activities and/or that can be used for treating liver diseases or for evaluating the efficacy, the metabolism, and/or toxicity of a compound.