The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 08, 2019
Filed:
Jan. 13, 2017
Applicant:
Southern Methodist University, Dallas, TX (US);
Inventors:
John G. Wise, Allen, TX (US);
Pia D. Vogel, Allen, TX (US);
Frances K. Brewer, Waxahachie, TX (US);
Courtney A. Follit, Dallas, TX (US);
Assignee:
Southern Methodist University, Dallas, TX (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5025 (2006.01); A61K 31/353 (2006.01); A61K 31/4196 (2006.01); A61K 31/4525 (2006.01); A61K 45/06 (2006.01); A61K 31/352 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5025 (2013.01); A61K 31/352 (2013.01); A61K 31/353 (2013.01); A61K 31/4196 (2013.01); A61K 31/4525 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells.